Loreto, a small town of Ancona Province, is known all over the world for its Sanctuary that makes it one of the most important places of pilgrimage and pray for the Catholics, together with Medjugorje and Lourdes. The believers go to Loreto to give prays of devotion to the ruins of the Holy House where Jesus lived in Nazareth.
http://www.visitancona.com/en/the-sanctuary-of-loreto-holy-house/